Olga Kraevaya

PhD thesis: “Rational design of functional fullerene derivatives: perspective materials for medicine and electronics”.

Supervisor:

IDC committee members: Prof. Timofei Zatsepin, Prof. Andriy Zhugayevych

Olga graduated from the Higher Chemical College of the Russian Academy of Sciences (Mendeleev University of Chemical Technology) in 2018. Her specialist diploma work was dedicated to the synthesis of the functional fullerene derivatives. In her current project, she works on the synthesis of novel organic materials for lithium ion batteries (LIB).

List of papers:

1. Ekaterina A. Khakina, Olga A. Kraevaya, Maria L. Popova, Alexander S. Peregudov, Sergey I. Troyanov, Alexander V. Chernyak, Vyacheslav M. Martynenko, Alexander V. Kulikov, Dominique Schols, Pavel A. Troshin. Synthesis of different types of alkoxy fullerene derivatives from chlorofullerene C60Cl6. Organic Biomolecular Chemistry, v.15, pp. 773-777 (2017).
2. Olga A. Kraevaya, Alexander S. Peregudov, Vyacheslav M. Martynenko, Pavel A. Troshin. Facile synthesis of isomerically pure fullerenols C60(OH)5Br and 1,4-C60(OH)2 from chlorofullerene C60Cl6. Tetrahedron Letters, v. 59, pp. 605-607 (2017)
3. Pavel A. Mikhailov, Olga A. Kraevaya, Alexandra Yu. Belik, Alexander Yu. Rybkin, Ekaterina A. Khakina, Nikolay S. Goryachev, Lubov I. Usol’tseva, Yu. V. Romanenko,  Oscar I. Koifman, Olga I. Gushchina, Andrey F. Mironov, Pavel A. Troshin, Alexander I. Kotel’nikov. Synthesis, photophysical properties, and photochemical activity of the water-soluble dyad based on fullerene С60 and chlorin e6 derivatives. Doklady Physical Chemistry, v. 6, pp. 477 (2017)
4. Irina Avilova, Ekaterina Khakina, Olga Kraevaya, Alexander Kotelnikov, Raisa Kotelnikova, Pavel Troshin, Vitaliy Volkov. Self-diffusion of water-soluble fullerene derivatives in mouse erythrocytes. BBA Biomembranes, v. 8 (1860), pp. 1537-1543 (2018)
5. Alexander Rybkin, Alexander Kotelnikov, Dmytro Volyniuk, Juozas V. Grazulevicius, Olga Kraevaya, Alexandra Belik, Ekaterina Khakina, Alexander Zhilenkov, Nikolay Goryachev, Pavel Troshin. Covalently-linked water-soluble fullerene-fluorescein dyads as highly efficient photosensitizers: synthesis, photophysical properties and photochemical action. Dyes and Pigments, v. 160, pp.457-466 (2018)
6. Ning Lou, Olga Kraevaya, Pavel Troshin, Liangbing  Gan. Synthesis of Pentapyrazolyl, Pentapyrrolyl, and Pentaanilino C60 Derivatives. Synthesis, v.50, pp. 4283-4289 (2018)
7. Alexandra. Y. Belik, Igor V. Kukushkin, Alexander. Y. Rybkin, Nikolay S. Goryachev, Pavel A. Mikhailov, V.S. Romanova, Olga A. Kraevaya, Pavel A. Troshin, Alexander I. Kotelnikov. Application of SERS and SEF Spectroscopy for Detection of Water-Soluble Fullerene-Chlorin Dyads and Chlorin e6. Doklady Physical Chemistry, v. 481, pp. 95-99 (2018)
8. Vasilina Sergeeva, Olga Kraevaya, Elizaveta Ershova, Larisa Kameneva, Elena Malinovskaya, Olga Dolgikh, Marina Konkova, Ilya Voronov, Alexander Zhilenkov, Natalia Veiko, Pavel Troshin, Sergei Kutsev, Svetlana Kostyuk. Antioxidant Properties of Fullerene Derivatives Depend on Their Chemical Structure: A Study of Two Fullerene Derivatives on HELFs. Oxidative Medicine and Cellular Longevity, Article ID 4398695 (2019)
9. A. G. Bobylev, O. A. Kraevaya, L. G. Bobyleva, E. A. Khakina, R. S. Fadeev, A. V. Zhilenkov, D. V. Mishchenko, N. V. Penkov, I. Yu. Teplov, E. I. Yakupova, I. M. Vikhlyantsev, P. A. Troshin. Anti-amyloid activities of three different types of water-soluble fullerene derivatives. Colloids Surf. B, v. 183, pp. 110426 (2019)
10. O. A. Kraevaya, A. S. Peregudov, S. I. Troyanov, I. Godovikov, N. E. Fedorova, R. R. Klimova, V. A. Sergeeva, L. V. Kameneva, E. S. Ershova, V. M. Martynenko, S. Claes, A. A. Kushch, S. V. Kostyuk, D. Schols, Alexander F. Shestakov, P. A. Troshin. Diversion of the Arbuzov Reaction: Alkylation of C-Cl Instead of Phosphonic Ester Formation on the Fullerene Cage. Org. Biomol. Chem., v. 17, pp. 7155-7160 (2019)
11. C.-W. Wong, A. V. Zhilenkov, O. A. Kraevaya, D. V. Mischenko, P. A. Troshin, S.-h. Hsu. Toward Understanding the Antitumor Effects of Water-Soluble Fullerene Derivatives on Lung Cancer Cells: Apoptosis or Autophagy Pathways? J. Med. Chem., v. 62 (15), pp. 7111-7125 (2019)

List of conferences:

1. Olga A. Kraevaya, Alexander S. Peregudov, Alexander V. Chernyak, Vyacheslav M. Martynenko, Pavel A. Troshin. DMSO-promoted synthesis of a series of C₆₀(OR)₅Cl derivatives from C₆₀Cl₆ (Poster). European Materials Research Society Spring Meeting 2016. Lille, France (2016)
2. Olga A. Kraevaya, Alexander S. Peregudov, Sergey I. Troyanov, Alla A. Kushch, Dominique Schols, Pavel A. Troshin. Synthesis and antiviral activity of novel polycarboxylic fullerene derivatives (Poster). Trends in Influenza Research. Saint-Petersburg, Russia (2017)
3. Olga A. Kraevaya, Alexander S. Peregudov., Sergey I. Troyanov., Alla A. Kushch, Dominique Schols, Pavel A. Troshin. Design of thiophene-based water-soluble fullerene derivatives and their antiviral properties (Poster). European Materials Research Society Spring Meeting 2017. Strasbourg, France (2017)
4. Olga A. Kraevaya, Alexander S. Peregudov, Sergey I. Troyanov, Alla A. Kushch, Dominique Schols, Pavel A. Troshin. Novel water-soluble fullerene derivatives with promising antiviral properties (Poster). European Materials Research Society Spring Meeting 2018. Strasbourg, France (2018)
5. O. A. Kraevaya, A. S. Peregudov, S. I. Troyanov, A. A. Kushch, D. Schols, P. A. Troshin. Antiviral properties of the novel water-soluble fullerene derivatives (Oral talk). E-MRS Fall Meeting 2019. Warsaw, Poland (2019)
6. O. A. Kraevaya, E. A. Khakina, A. V. Zhilenkov, A. A. Kushch, T. Zatsepin, J. Balzarini, D. Schols, P. A. Troshin. Exploring water-soluble fullerene derivatives as potential antiviral pharmaceuticals (Invited talk). E-MRS Fall Meeting 2019. Warsaw, Poland (2019)
7. O. A. Kraevaya, A. S. Peregudov, S. I. Troyanov, A. A. Kushch, D. Schols, P. A. Troshin.Novel water-soluble fullerene derivatives with promising antiviral properties (Poster). XXI Mendeleev Congress on General and Applied Chemistry. Saint-Petersburg, Russia(2019)
8. O. A. Kraevaya, A. V. Mumyatov, A. F. Shestakov, K. J. Stevenson, P. A. Troshin. Novel redox-active materials for batteries based on fullerene derivatives and quinizarine (Poster). E-MRS Spring Meeting 2019. Nice, France (2019)