Student | PI | Thesis Title |
Danchurova Anastasia | Dmitri Pervouchine | Auto- and cross-regulation of splicing factors via alternative splicing coupled with nonsense-mediated decay (AS-NMD) |
Mikova Valeriya | Dmitri Pervouchine | A study of intronic polyadenylation and splicing in hepatocellular carcinoma |
Trankova Natalia | Dmitri Pervouchine | Small bacterial noncoding RNAs as antisense regulators of gene expression |
Pak Marina | Dmitry Ivankov | Study of influence of homology modeling on the prediction of protein stability change upon mutation |
Dzhafarov Mais | Ekaterina Khrameeva | Genotype by sequencing approach for population analysis and prediction of heterotic groups in maize (Zéa máys). |
Bokan Bella | Philipp Khaitovich | Genome-wide association study of pork lipid composition |
Doronin Danila | Philipp Khaitovich | Gene expression analysis in 35 brain regions in control human individuals and schizophrenia patients |
Velikanova Anastasiia | Philipp Khaitovich | Systematic analysis of age-dependent lipidome alterations in rat tissues |
Lukyanov Daniil | Dmitriy Chudakov | Functional differences of tumor-infiltrating B cells associated with antibody isotype |
Grinchenko Andrei | Mikhail Gelfand | Molecular mechanisms modulating the fate of neural stem cells cultivated on bioengineered matrices based on modified pectins |
Dranenko Natalia | Mikhail Gelfand | Deep reconstruction of evolution of protein families |
Edema Hilary | Mikhail Gelfand | Comparative genomic analysis of lignin degradation and its transcriptional regulation in Streptomyces spp. |
Grigorashvili Elizaveta | Mikhail Gelfand | Feature extraction by a neural network trained to predict RNA structure |
Djamalova Dilfuza | Mikhail Gelfand | Re-classification of species and genera in family Bacillaceae |
Karelin Anton | Mikhail Gelfand | Analysis of PTCL heterogeneity and RNA-based classification of subtypes |
Rybina Anna | Mikhail Gelfand | Functional and phylogenetic analysis of the Escherichia coli yih-gene cassette involved in the 6-sulfo-D-quinovose and lactose degradation pathways. |
Stelmakh Viktoriia | Mikhail Gelfand | Computational methods for analysis of Danio rerio behavior in Novel tank test as a tool for screening of pharmacological agents. |
Shikalov Aleksandr | Timofei Zatsepin | Comparison of specificity in unwinding of secondary structures in mRNA by eukaryotic RNA helicases DDX3, eIF4A, DHX29 |
Kopnin Ilia | Timofei Zatsepin | New chemical modifications in RNA for improved CRISPR-Cas9 genome editing system |
Kramarev Igor | Konstantin Lukyanov | Multicolor cell labeling for tracking clones of mammalian cells |
Rukh Shah | Konstantin Lukyanov | Genetically encoded epigenetic probes for live-cell fluorescence microscopy and mapping of histone 3 modifications |
Lisevich Irina | Petr Sergiev | Deciphering the mechanism of action of the bacterial translational inhibitor synthesized by Actinoplanes sp. 49252 |
Halimani Noreen | Yuri Kotelevtsev | RNA interference as a useful tool for liver macrophage polarization |
Ivanova Yulia | Yuri Kotelevtsev | Microdystrophin modification for T-cell epitope elimination |
Popov Aleksandr | Svetlana Dubiley | Study of linear phosphorylated peptide (LPP) from Paenibacillus alginolyticus |
Buianova Elizaveta | Konstantin Severinov | Construction of ribosome mutants with cysteine residues exposed into the nascent peptide exit tunnel |
Anton Shkaruta | Konstantin Severinov | The analysis of potential inhibitors of CRISPR-Cas system in the human pathogen Clostridium difficile |
Anastasia Batyreva | Konstantin Severinov | The role of Cold Shock Domain proteins in the regulation of growth, development and low-temperature stress adaptation in Arabidopsis thaliana |
Chaban Anastasia | Maria Sokolova | Function of two non-canonical RNA polymerases of Thermus bacteriophage P23-45 |
Drobysheva Arina | Maria Sokolova | Transcriptional strategy of the crAss-like phage phi14:2 |
Misovetc Inna | Maria Sokolova | Investigation of virion RNA polymerase of giant bacteriophage AR9 |
Kriukova Valeriia | Dmitriy Chudakov | Shaping naive TCR repertoires in mice |
Abiko Brendah | Eugene Lysenko | Specificity of cadmium effect on the photosynthetic apparatus in barley (Hordeum vulgare L.) |
Samolygo Aleksei | Konstantin Severinov | The functional and structural analysis of Marinitoga piezophila Csx1-Crn2 protein |
Elizaveta Miticheva | Konstantin Severinov | Protein-protein and protein-DNA interactions of components of type 1 BREX systems |
Colomina Laura | Konstantin Severinov | Structure-functional analysis of the role of the Escherichia coli subtype I-E CRISPR-ACas system Cas1 protein in spacer adaptation |
Yasinskaya Anna | Konstantin Severinov | Adaptation by Type III CRISPR-Cas of Thermus thermophilus during infection by bacteriophage phiKo |
Smirnov Sergei | Konstantin Severinov | Effects of changes in type II restriction-modification system Esp1396I enzymes concentrations on protection from phage infection |
Zhigulev Artemy | Mikhail Gelfand | Regulation of Drosophila Xrp1 gene by p53-dependent enhancer 75C6 |
Student | Pi | Thesis Title | Presentation |
Bogdan Kirillov | Ekaterina Savitskaya | Interpretable evaluation of Cas9-gRNA and Cpf1-gRNA specificity to on-targets and off-targets via Deep Learning | |
Mariia Vlasenok | Konstantin Severinov | Regulation of genome-wide transcription by essential factors that control promoter-proximal RNA polymerase II pausing in human cells | 1-vlasenok_mariia_18june |
Matvei Kolesnik | Konstantin Severinov | Matvei Kolesnik Konstantin Severinov Off-target degradation of cellular RNA by CRISPR-Cas13a nuclease: evidence of the involvement of RNA-targeting toxins | |
Alena Drobiazko | Konstantin Severinov | The Study of BREX System Proteins Functions | 4-drobiazko-alena-18-06-2019 |
Karyna Karneyeva | Konstantin Severinov | A study of bacteriophage infection processes in the presence of Type III CRISPR-Cas mediated defense | |
Ivan Fedorov | Ekaterina Savitskaya | Detection of rare CRISPR adaptation events by suppressing PCR | |
Laura Chacon Machado | Ekaterina Savitskaya | The role of NHEJ double-strand break repair on sgRNA/Cas9 targeting in Pseudomonas putida KT2440 | |
Polina Muziukina | Ekaterina Savitskaya | Evaluation of CRISPR spacers diversity in Clostridium difficile clinical isolates | 8-muzyukina_18-06 |
Aleksandr Kirillov | Konstantin Severinov | The influence of copy number of restriction-modification genes on protection from viral infection | |
Eldar Yagmurov | Svetlana Dubiley | The study of putative mcc-like gene cluster from Hyalangium minutum | |
Stepan Ovchinnikov | Svetlana Dubiley | Study of type II GNAT toxin-antitoxin systems | |
Valeriia Mitsurova | Konstantin Severinov | Studying the involvement of autophagy in the response of A. thaliana to M. persicae attack | |
Anastasiia Stepanova | Konstantin Severinov | Leafy head development of Chinese cabbage | 6-stepanova_anastasiia_19_june |
Aleksandr Polkhovskii | Konstantin Severinov | Characterization of telomerase machinery components in Brassicaceae family | |
Sergei Bogomolov | Konstantin Severinov | Antimicrobial phytochemicals from edible and medicinal plants | 8-bogomolov-sergei-19_06_2019 |
Alevtina Koreshova | Georgii Bazykin | Phylogeographic analysis of hepatitis A virus in Russia | |
Anna Obraztsova | Mikhail Shugai | Bioinformatic analysis of memory B cell receptor repertoires with an improved algorithm for lineage tree reconstruction | |
Anna Zhdanova | Georgii Bazykin | Digging the genomes of spontaneously aborted embryos for Mendelian pathogenic traits | |
Bogdan Kirillov | Ekaterina Savitskaya | Interpretable evaluation of Cas9-gRNA and Cpf1-gRNA specificity to on-targets and off-targets via Deep Learning. | |
Denis Moiseenko | Dmitriy Chudakov | Finding signatures of viral infection in T cell repertoire sequencing data | |
Egor Semenchenko | Georgii Bazykin | Evolution of germline mutational spectra among great apes | |
Grigorii Sukhorukov | Georgii Bazykin | Recombination in tick-borne encephalitis virus | |
Arsenii Pozdyshev | Mikhail Gelfand | A microbiome-based approach for oil-well inflow determination | |
Nurislam Shaikhutdinov | Georgii Bazykin | Population genomics of the sleeping chironomid (Polypedilum vanderplanki) | |
Olga Gavrilenko | Philipp Khaitovich | Human-specific lipidome features in anterior cingulate cortex and cerebellum based on mass-spectrometry analysis | |
Matvei Bulat | Philipp Khaitovich | Evolutionary novel cell phenotypes in human anterior cingulate cortex revealed by single cell transcriptomics | |
Yuliya Sarana | Mikhail Gelfand | Comparative analysis of aphid microbiomes | |
Sergei Slavskii | Georgii Bazykin | Analysis of human height as a complex trait using the UK Biobank megacohort | |
Svetlana Kalmykova | Dmitri Pervouchine | Impact of somatic mutations disrupting RNA structure on alternative splicing | |
Julia Shaykhutdinova | Mikhail Gelfand | A biology-based mathematical model of immunotherapy for murine syngeneic tumor models | |
Olga Isaeva | Dmitriy Chudakov | Influence of immunotherapy and prognostic significance of lymphocytes in tumor microenvironment | |
Vladislav Belousov | Mikhail Shugai | Studying interactions between alpha and beta chains of the T-cell receptor and alpha-beta pairing preferences | |
Filipp Sergeev | Timofei Zatsepin | Downregulation of adenosine N6-methylation in RNA contributes to rRNA processing | |
Mariia Nazarova | Timofei Zatsepin | Development of CYTOR and MIR4435-2HG lncRNAs knockout cell lines and study of a unique 2HG-216 transcript in vitro. | |
Sofia Kamalian | Mikhail Gelfand | Characterization of the functional role of the CTCF terminal domains | |
Grigorii Perelman | Yuri Kotelevtsev | Discovery of signaling pathways involved in downregulation of hyaluronan and collagen | |
Kirill Danilov | Yuri Kotelevtsev | In vitro efficacy assessment of AAV based vectors for the gene therapy of Duchenne muscular dystrophy | |
Kulash Zhumadilova | Evgeny Nikolaev | Identification of lipid markers of human brain gliomas by using accurate mass measurements and MS/MS technique in mass spectrometry imaging | |
Tinashe Prince Maviza | Petr Sergiev | Biochemical and Structural Characterization of Tetracinomycin X – a Novel Translational Inhibitor | |
Mahmoud Badawi Youssef Gouda | Philipp Khaitovich | Region-specific features of the сortical architecture unique to the human brain | |
Marina Makharova | Dmitriy Chudakov | The role of LDB1 in the regulation of antibody maturation in B cells | |
Svetlana Khorkova | Dmitriy Chudakov | Study of trans-chromosomal inserts in immunoglobulin genes | |
Anna Egorova | Olga Dontsova | Functions of L116 small mitochondrial polypeptide in mouse fibroblasts | |
Oleg Baranov | Olga Dontsova | Processing and localization of telomerase RNA | |
Gurchenko Elena | Philipp Khaitovich | Genome-Wide Association Studies (GWAS) for agronomically important traits loci in Russian Sunflower germplasm |