The Life Sciences educational program supports Masters and PhD students academic mobility both inside and outside Russia. Academic mobility research is performed as part of thesis research and is carried under the supervision of Skoltech faculty and co-supervision by the academic mobility host. Some examples of academic mobility placements and projects are listed below.
During my mobility program I am doing research in University of North Dakota (UND). It is located in United States, North Dakota, in Grand Forks. I am studying the regulation of transcription cycle in eukaryotes at the early stages. The laboratory I am working at employs nascent RNA sequencing method, providing a great opportunity to study the stages of transcription by mapping active RNA polymerase positions with a single nucleotide resolution.
There are many international students in the lab.Most of them are Indian, there are also people from France and several African countries. The atmosphere is nice and friendly, everyone is glad to help you and ask you for some help, too.
The international lab members often get together to celebrate birthdays and national holidays.
UND campus covers about 1/7 area of Grand Forks. There are fifteen thousand students in the university, with town population being only about 50 thousand people.
The campus has many nice places to study and work outside the lab: several libraries, cafes and auditoriums, accessible for students at any time of day.
Personally, I am fond of the architecture of the campus: the warm colored halls sometimes resemble castles.
Still, the place feels very American. For example, it’s mandatory for graduate students association to bring a couple of boxes of donuts to faculty lectures. Looks like it’s considered to make people come to the lectures. Also, people here are very proud of the university and its local hockey team. It is possible to buy literally anything with its logo in a bookstore in campus. Yes, that is the BOOKstore in the picture.
The climate is very alike to Moscow. With slightly stronger winds and lower temperature. But in small town it is easier to enjoy nature, which is beautiful here .
NCBI is among the largest Bioinformatics research centers in the world and has probably the largest collection of biological data humankind gathered so far. It is a part of National Institutes of Health – main US federal agency responsible for biomedical and public health research. My supervisor at NCBI is the Group’s leader, Dr. Eugene Koonin, one of the most cited researchers of Russian origin, the author of “Logic of Chance” – the best selling book on the theory of evolution.
During the internship I am working on constructing a Machine Learning-powered approach to look for defense islands in bacterial genomes. I use various supervised and unsupervised models to build up towards a more-less general solution for that task potentially working as an algorythm. The data I use are diverse, ranging from a set of annotated genomes to protein sequences with various kinds of metadata. The only equipment I need for my work is considerable computational power to train the models and that is exactly what is easily available at NCBI: the servers and machines with powerful GPUs are the best one can dreamof.
I really enjoy working in this lab, it is both inspiring and challenging, the way research is organized here balances well the freedom of scientific inquiry and the necessity of getting things actually done. I’m really grateful to all of my colleagues and supervisors both at NCBI and at Skoltech for their advice, help and the overall attitude towards doing the best job we can.
I am the 2nd year master student at Skoltech. I work in the science centre “Nonabio” and the goal of my project is to study how bacteriophages overcome the protective system of bacteria. During this project, I have the opportunity to work in Dr. Zeng lab in Texas A&M University. This university is one of the biggest in the US and has a long history There is also a town nearby College Station . This is an interesting town as it literally appeared from the university, attracting both students and workforce to settle around. . There is also a very interesting library on the territory of this university – George Bush library where he has been recently buried. The significant advantage that I can work in the lab for 24 hours and also on the weekend, and it helps to do more and more experiments.
I’m living in Highland Park, NJ – the small town near Rutgers University. On weekends and holidays I’m trying to explore NY and NJ together with native speakers. I celebrated Thanksgiving day, Christmas and New Year in a good company of new American friends.
In our Lab we have 23 members and it is really an International Lab, because 23 people presented by 13 nationalities. We have 6 graduated students (including me) and 5 undergraduate students (not presented in photo, because they are not lab members). Ilya Raskin Laboratory belongs to Plant Biology department of Rutgers University and is the basis for GIBEX Institute (Global Institute of BioEXploration). My project is about searching the plant antimicrobial compounds from edible and medicinal plants. The Lab is fully equipped for conducting any research connected with plant and cell biology.
I traveled to the United States for the first time, which was quite an unusual experience, especially since I lived there for six weeks. Chicago is located on the shore of one of the Great Lakes, particularly, Lake Michigan, which is so huge that it looks like an entire sea. I really enjoyed bike riding along the lake shore. I also found time to travel to Boston on weekends and visited Manhattan during a twelve-hour stop on my flight home. Thus, I could see how diverse America is in different parts of the country.
I believe that, the mobility program at Skoltech is a great opportunity to get valuable professional knowledge and international experience, as well as to compare how science works in different parts of the world, and certainly to have fun.
I was lucky to work in MIT for 11 months. I lived in Somerville, at an 11-minute bike ride from the lab, a luxury that is impossible in Moscow, for the time being at least. To make most of my stay, I worked very hard, spending most of my time in the lab, but I also took the time to visit some of the important places in Boston such as the Harvard Arboretum, the Museum of Science and of course, I made a few trips to Cape Cod to spend time on the beach.
A lab is like a kitchen, so it does not take too much time to find the logical places where things are kept. I easily adapted to the Anderson lab and benefited highly from the trainings offered in the institute. However, wherever I go, the most important thing for me is the people that surround me. I especially appreciated the level of energy: everyone is very focused and they work hard. It’s very stimulating when you see all the good results around you, even those acquired through sweat and tears! I made a few friends there, and I miss them already.
On the scientific side, the few months I spent in MIT were very fruitful. I obtained some important results for my PhD projects, and I was able to perform some experiments for other projects of Dr Zatsepin’s lab.
Overall, I would definitely recommend Academic mobility, provided that the project is well designed to take advantage of it, because any experience in another country, another culture, another lab for that matter, is the equivalent of seeing life from another angle. It gives perspective, it makes you grow, and it challenges you to push yourself beyond what you think you can do.
For almost a year and a half I’ve been working on my PhD at Rutgers University in the USA. Rutgers is a huge public university with more than 60 thousand students enrolled (to compare: there are about 40 thousand students at Moscow State University). Rutgers has a wide-spread presence in the state of New Jersey with the largest campus located in New Brunswick . The New Brunswick campus is further divided into five small sub-campuses including the Busch Campus where I have been doing my research at Waksman Institute of Microbiology under the supervision of Prof. Konstantin Severinov and Prof. Bryce Nickels. During my trip, I’ve been studying CRISPR-Cas systems, the adaptive immune systems of prokaryotes.
In short, bacteria are able to keep memories of viruses they fought by inserting short pieces of viral DNA, spacers, into the bacteria’s own genome. These memories ensure that if the bacteria get infected by the same virus again the cells “know” how to vanquish their enemy. We were trying to understand how the memories are generated by analyzing sequences of spacers incorporated into bacterial genomes and sequences of short DNA fragments preceding spacers, prespacers, that float in cytoplasm before they get inserted into a chromosome. We have described a typical prespacer in two types of CRISPR-Cas systems and our paper reporting these results is currently under review. So, as far as science is concerned, I think my trip has been very successful so far. And I really enjoy working at Waksman Institute for multiple reasons. Firstly, the people have really gone out of their way to help me! Furthermore, I am impressed by how well everything is organized here, whether it be lab supply orders or waste disposal. In addition, there are small events like “tea time” every two weeks when the whole institute gets together to have some cookies, coffee and tea. There are also bigger events like picnics or Christmas parties. I think all these events make the atmosphere more friendly and less formal which goes a long way to creating a very pleasant working experience that I found in the institute.
There are several public holidays in the USA. They are often on Mondays so you have long weekends and can use this time to go on a short trip. I have visited several places in the US like New York; Washington, D.C.; Orlando and the Tampa Bay Area in Florida; Las Vegas and the surrounding fantastic neighborhoods in Nevada and Arizona. I went to a classical music concert in Princeton and listened to a Grammy-winning gospel choir in Brooklyn. I was trick-or-treating on Halloween and was running away from zombies at a “haunted” cornfield. I was eating turkey on Thanksgiving and was belly dancing at Arabic parties. There were so many events! I am so happy I got to experience all of this! Even though organizing the trip, getting a visa and looking for a place to stay might be frustrating, the experience you gain is totally worth it!
I ам a second-year Master student of “Life Science” program. My academic mobility internship is going on in the Vienna Biocenter (VBC), Austria. This huge center includes four research institutes and several biotechnology companies. Together with Rushad Pavri group from Institute of Molecular Pathology, we are trying to reveal some features of the latest stages of antibody diversification regulation/ In other words, to answer the question what mechanisms make AID-dependent mutations so specific to immunoglobulins loci. I should say, the atmosphere in the lab, as well as in the whole institute, is highly supportive, comfortable and inspiring, which makes the process of scientific work much more engaging.
The first thing, which I noticed was a very intensive collaboration between research groups. Even though each of them works on completely different research problems, a collaboration between groups, multiple discussions and meetings often lead to new ideas, giving a fresh view on your project. And such VBC tradition like a “Beer hour” every Friday at 17:00 significantly facilitates fruitful networking :D. Another notable feature of VBC is it’s infrastructure and a variety of different facilities with most advanced equipment: NGS, Advanced microscopy, electron microscopy, metabolomics, histopathology, and other facilities, usage of which is available for all groups, after passing an appropriate training. Every week the institute invites outstanding scientists to give a talk or seminar. And almost every research they tell us about is a high quality work with a portion of scientific romantics, full of struggling and pain, but at the end turning into a beautiful story. How is that possible not be fascinated by that?
I am a second-year master student. My current supervisor is Konstantin Severinov and I work in Institute of Gene Biology RAS. During my thesis project work I had an internship in Institute of Pasteur (Paris, France) under the leadership of Dr. Krupovic (Molecular Biology of Gene in Extremophiles Laboratory, Department of Microbiology).
The main research axis of this team is studying viruses of hyperthermophilic bacteria and archaea. These viruses are diverse and have many unique features, setting new challenges for fundamental studies. Moreover, it is necessary to explore these highly stable viruses to probably harness them in biotechnology. The Pasteur Institute is one of the world’s leading research centers with a great history. I was very lucky to have such an experience in the extremely friendly and inspiring surrounding. I am very grateful to the team for sharing their skills, knowledge and providing me a wonderful opportunity to work together.
My name is Eldar Yagmurov, I am a second-year master student of Skoltech’s Life Science program. As a mandatory part of Skoltech’s master program, I am completing my thesis project under the supervision of Prof. Konstantin Severinov. I am investigating the Microcin C (McC) – producing cluster from Hyalangium minutum. In my thesis, I have managed to study and validate the mechanisms of McC production from H. minutum mcc cluster. The most exciting part of my project was the discovery of H. minutum self-immunity protein, which is able to inactivate McC and McC-like compounds. To understand the mechanisms and structure of McC inactivating protein from H. minutum, I had to complete an internship in the laboratory with powerful analytical facilities. So, I travelled to France to complete my mobility program under the supervision of Prof. Guy Lippens, in the Laboratoire d’Ingénierie des Systèmes Biologiques et des Procédés (LISBP), Toulouse. LISBP is a an un-to-date and well-equipped laboratory running a diverse range of cutting-edge research projects, ranging from metabolomics projects to the projects aimed at improving agriculture worldwide.
My internship in Toulouse is very important for me not only from the scientific point of view but also from invaluable life experience I got here. I have never lived in Europe longer than for a week, and I must admit that this is one of the best experiences of my life. I find France and its people to be very open-minded, warm and kind-hearted. Every morning on my route to the lab, I hear “Bonjour! Ça va?” from complete strangers; when I have difficulties finding my ways around the city I never hear “no” as an answer/ Instead people are eager to help. I was even once given a croissant for free in the local boulangerie, which was very nice since the pastry here is magnificent. To add more to the food topic, I had a very unexpected discovery, while always holding some prejudice towards cheese, here, I realized that I am in love with it. Another surprising aspect of France is that people here cherish nature around themselves, they stay close to it and try their best not to harm it. French are famous for their relaxed pace of life void of rush and hurry, and, from my point of view, Toulouse is one of the best cities to experience the typical French way of life. The city is filled with beautiful architecture, numerous street cafes, the wonderful scent of freshly baked pastry, medieval streets and squares, and, of course, the warm weather of the south of France. You can even see the Pyrenees on a clear day. Not to mention the beautiful language people speak here, which I have the pleasure of practicing and improving. Overall, I find this experience to be fulfilling and exciting.
Together with Prof. Lippens and the members of his team, I investigate the catalytic mechanisms of McC inactivation by H. minutum self-immunity protein with help of Quantitative Nuclear Magnetic Resonance Spectroscopy. The technique allows for precise and real-time analysis of different biomolecules on a very small time-scale. In parallel, we are studying the crystal structure of the same protein using the x-ray diffraction method. My colleagues from LISBP, whom I am extremely grateful to, are always there to help and explain whenever I have difficulties with something. Moreover, the lab has a very cozy tradition of having lunch together, this gives an opportunity to discuss our projects and usually get helpful insights and comments.
In conclusion, I want to say that my mobility in LISBP, Toulouse is a very important chapter of my life. Not only it allows me to see how a world-renowned laboratory works and establish useful network connections; it also allows me to broaden my horizons and to see the world differently. I am extremely grateful to Skoltech and my research advisors for providing me with such a great opportunity to pursue the mobility program in France.
I was on academic mobility at Max Delbrück Center for Molecular Medicine in Berlin. Berlin is a vibrant city combining both history and modernity. There are so many museums, theatres, and clubs in Berlin that anybody would find something for himself. Scientific life at MDC was also full of events such as conferences and seminars. And I can say, I reallyenjoyed my stay in Berlin.
At the moment I arrived, de la Rosa lab was a small research group, so when I joined them I didn’t feel myself as a guest, I immediately became part and parcel of the team. We were studying insertions in immunoglobulin genes, and my part of the work was to search for insertions in Ig light chain.
In the laboratory, I studied the cell line that was obtained from the so-called “sleeping” chironomid embryos (a specie of the midge from the Chironomid family). They have an exeptional capacity to withstand severe drought. The cell line can be stored in a dry state after desiccation at room temperature for up to 251 days and can return to the physiological activity during rehydration with retaining proliferation potential.
This laboratory have developed the method for reproducing of a midge in the laboratory conditions and support its life cycle for many years based on midge’s amazing ability to stop metabolism and return to active life. So the laboratory focuses on studying the mechanisms of this process .
An interesting effect of the midge’s and cell line feature is that in the process of desiccation, genomic DNA gets fragmented through a variety of double-stranded breaks and they can lead to various genomic rearrangements at break points during DNA reparation.
In addition to working in the laboratory, my colleagues and I climbed to Mount Tsukuba, that is not so high as Mount Fuji, but you can still get tired during climbing to the top. We also visited some popular places in Tokyo, where we tasted the local cuisine and joined the local culture.
The staff of the laboratory I worked with stuck me with thier diligance and responsible approach to any issue. These, probably typically Japanise, qualities were especially noticeable in the almost round-the-clock work schedule in the laboratory, productive scientific seminars and the absence of any significant attention to the earthquakes.
I am grateful to the lab where I worked, and my supervisors for the opportunity to study such an unusual biological object, which still attracts the attention of biologists from different countries.
I was very happy to catch a glance of warm and dry autumn here It was one of the best autumn in my life! Moreover, in the morning a mystical and wonderful mist, laid down on hills and trees’ crowns to vanish just in few hours disclosing tawny leaves and sunny streets . All this creates relaxed and calmed mood inside of you.
My mobility trip was to Perugia, Italy. It is a lovely place, which feels like a breath of fresh air after noisy and smoggy Moscow. There are many trees, parks and very beautiful historical buildings, which are literally everywhere.
My colleagues in a lab were very friendly and ready to help. When you come into a new environment, you feel a little bit constrained or embarrassed, but I did not feel anything like that, because of everyone helped me in case, I did not know where some reagents or equipment is. People in Italy are very friendly and always want to help you in case of need, even if you do not understand each other. Yes, it is a sad truth – if you do not know Italian, it is hard to communicate there, especially, when you are outside of touristic places and beaten tracks . On the other hand – it is a great stimulus to learn the local language.
Now, we are continuing to process the the data, obtained during experiments, especially FACS data and Western blot data. In In addition, we are going to continue with some RT-qPCR probes for further characterization of fibrosis processes inside the murine liver.As for my scientific results, we have done the histology part of work – stained the liver tissue samples for leukocytes infiltration and collagen for evaluation of fibrosis and inflammation heaviness. We performed FACS part – counted leukocytes amount in each sample and divide them into different groups (T-cells, macrophages, NK-cells etc.) for the definition if there any difference in cells type ratio or not. In addition, we performed standard molecular biology techniques like RT-qPCR and Western blot to reveal if there any changes in different proteins or RNAs expression during the fibrosis in control and GILZ-KO group or not.
Overall, it was productive time, especially due to the atmosphere, which contributes to a calm, work-centered mindset and provides the necessary rest between work sessions.
In October, 2018 I started my MSc Thesis research in Tzin lab of Ben-Gurion University in Negev. The university is located in the center of Israel and is made up of two parts – the main campus in the city Beer Sheva and another campus in the village Midreshet Ben-Gurion. The laboratory I studied in is situated in a small agricultural campus. It mainly focuses on studying of molecular plant-insect interactions. Lab members are postdoctoral fellows, Ph.D and MSc students from various countries: Israel, India, Ghana, Kazakhstan, Russia; so the main language in our lab is English. My co-advisers in Israel are Vered Tzin, a head of Tzin lab, and Hadas Zehavi, a research associate in Weizmann Institute of Science in Rehovot, Israel, who invited me to participate in a big project to study the role of authophagy in plant-insect interactions on Arabidopsis and green peach aphids. I sowed and grew Arabidopsis plants in lab conditions, infested grown plants with aphids, maintained aphid population, made choice analysis in Petri dishes and reproduced new seed for generation. These approaches are not the final part of my mobility, for the next 3 months I will conduct RT-qPCR, Western blotting, confocal microscopy and metabolite analysis to examine project hypothesis.
All the members in our lab are more than coworkers, they are a team: every 2 weeks we have a lab meeting where one of the members is talking about either an interesting article, process, or discovery in science related to our field of research. Once in a season we go to a wonderful place in Israel . Lately we have visited Yeruham park to see the crocus flowers in the desert. The Lab supervisor always keeps us informed about future conferences and workshops in Israel. We celebrate birthdays, memorable dates and festivals together. I am really grateful to my colleges for suggestions and technical support during my mobility period.
I am living in the university campus in a special dorm and it provides perfect facilities for comfortable life: sport (running, workout, boxing, football, volleyball, frisbee), dance (student’s salsa, professional salsa), performance (concerts, festivals, cultural evenings) and entertainment (pool, table tennis, table football, karaoke, hiking, choir) activities. One famous and highly illustrious festival here is the Cultural festival at the end of the year, I visited in end of December, 2018. It was an amazing concert with performances from different countries. I also enjoyed Chinese, Indian, Israeli and Russian food.
I think Ben-Gurion University in Negev is a good place for studying and research.
My name is Alena Drobiazko, and I am a second year Master student. To perform the experiments for my thesis, I went to work at the Department of Protein – DNA Interactions in Vilnius University, Lithuania under the supervision of Prof Dr Virginijus Siksnys. This lab works with enzymes. They study their structural and functional characteristics Particularly, the laboratory studies the enzyme assemblies contributing to the bacteria defence systems against viruses.
Vilnius University is one of the oldest European universities in the center of Old Town. However, the laboratory of Dr Siksnys is located in the modern building of Vilnius University Life Sciences Centre which is about half an hour ride from the Old Town. The university campus is very comfortable; there are several cafes, lots of auditoriums and a huge library to study.
My mobility lasted seven months, so I had a wonderful opportunity to observeVilnius in different seasons.
I am working with a newly discovered BREX system being one of the complex bacterial defense strategies . The project aims to confirm the predicted functions of BREX proteins individually and in complexes with other components of the system. For that, I had to obtain large amounts of purified BREX proteins and conduct different biochemical assays.
I am lucky to work with the team of Dr Siksnys in such a supporting atmosphere. People always are ready to help whenever I ask questions or bump into some problems.
You don’t have to learn Lithuanian if you want to work here, everyone in the lab speaks English, and about one third knows Russian.
The lab has a good tradition of celebrating everyone’s birthday and some holidays together. Taking into account that about 40 people (including students) are working in the lab, the celebration occurs almost every week. The photo below is from Dr Siksnys birthday.
My name is Anastasiia, I am the 2nd year Master student and I am doing my thesis research work in Wageningen University and in Netherlands in plant breeding department, Growth and Development group. Wageningen university is the wonderful place for agricultural science.
They have a huge greenhouse complex with different innovative systems, where they grow and study all kinds of plants including the most exotic – even bananas!
They harvested real fruits from banana plants in December!
My research is related to Chinese cabbage studies, specifically the studies of leafy head formation in Chinese cabbage on morphological, cellular and molecular levels. Therefore, I spend a lot of time in the greenhouse, growing my plant material – cabbages in the middle of the winter.
I also have a lot of lab work and there is high quality equipment that I use for my research.
I am a MS student at prof. E. Nikolaev’s lab. From September till the end of December I had an internship at Maastricht Multi Modal Molecular Imaging (M4I) Institute, the Netherlands, led by Dr. Ron Heeren. M4I is a unique place where surgeons, biochemists and mass spectrometrists work side by side tackling biomedical questions of clinical importance. The institute is adjacent to the hospital that not only fosters collaboration with doctors, but also speeds the process of getting “precious” samples with unaltered molecular composition. During my internship I was trained in mass spectrometry imaging (MSI) of brain tissue, especially lipids.
We all know that a mass spectrometer as a very precise instrument / It can reveal molecular composition available in a very small concentration. However we can also collect molecular information on the localized spots within a tissue and assign a pixel to each. Later, we can reconstruct a full molecular image that will show the distribution of particular molecule within that tissue slice.
My training involved all the steps of this complex procedure, such as cutting mouse brain slices on cryotome, operating matrix deposition robotic system and ultimately using mass spectrometers to make a molecular picture of the brain tissue slice. I have experimented with different settings, tried different protocols and instruments to optimize sample preparation and get full brain images. The lab I worked in was well-equipped, had many international and local students and vibrant atmosphere. I am grateful to my mentor, graduate student Britt Claes for her enthusiasm and effort. I have had a good time in Maastricht, met new friends, explored Dutch museums and culture.