2021

• The limits of normal approximation for adult height. Slavskii SA, Kuznetsov IA, Shashkova TI, Bazykin GA, Axenovich TI, Kondrashov FA, Aulchenko YS. Eur J Hum Genet. 2021 Jul;29(7):1082-1091. doi: 10.1038/s41431-021-00836-7

• Genomic DNA i-motifs as fast sensors responsive to near-physiological pH microchanges.
  Turaev AV, Isaakova EA, Severov VV, Bogomazova AN, Zatsepin TS, Sardushkin MV, Aralov AV, Lagarkova MA, Pozmogova GE, Varizhuk AM.Biosens Bioelectron. 2021 Mar 1;175:112864. doi: 10.1016/j.bios.2020.112864. Epub 2020 Dec 2.PMID: 33309217

• Hematopoietically-expressed homeobox protein HHEX regulates adipogenesis in preadipocytes.
  Evseeva MN, Dyikanov DT, Karagyaur MN, Prikazchikova TA, Sheptulina AF, Balashova MS, Zatsepin TS, Rubtsov YP, Kulebyakin KY.Biochimie. 2021 Jun;185:68-77. doi: 10.1016/j.biochi.2021.02.011. 

• Silver(I)-mediated base pairing in DNA involving the artificial nucleobase 7,8-dihydro-8-oxo-1,N⁶-ethenoadenine.
  Schönrath I, Tsvetkov VB, Barceló-Oliver M, Hebenbrock M, Zatsepin TS, Aralov AV, Müller J.J Inorg Biochem. 2021 Jun;219:111369. doi: 10.1016/j.jinorgbio.2021.111369. 

• Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex.
  Ryazantsev DY, Myshkin MY, Alferova VA, Tsvetkov VB, Shustova EY, Kamzeeva PN, Kovalets PV, Zaitseva ER, Baleeva NS, Zatsepin TS, Shenkarev ZO, Baranov MS, Kozlovskaya LI, Aralov AV.Biomolecules. 2021 Sep 26;11(10):1409. doi: 10.3390/biom11101409.

• Barnase encapsulation into submicron porous CaCO₃ particles: studies of loading and enzyme activity.
  Yashchenok AM, Gusliakova OI, Konovalova EV, Novoselova MV, Shipunova VO, Abakumova TO, Efimova OI, Kholodenko R, Schulga AA, Zatsepin TS, Gorin DA, Deyev SM.J Mater Chem B. 2021 Nov 3;9(42):8823-8831. doi: 10.1039/d1tb01315g.
• Magnetic Nanoparticles as a Tool for Remote DNA Manipulations at a Single-Molecule Level.
  Nikitin AA, Yurenya AY, Zatsepin TS, Aparin IO, Chekhonin VP, Majouga AG, Farle M, Wiedwald U, Abakumov MA.ACS Appl Mater Interfaces. 2021 Mar 31;13(12):14458-14469. doi: 10.1021/acsami.0c21002. Epub 2021 Mar 19.

• Indocyanine green dye based bimodal contrast agent tested by photoacoustic/fluorescence tomography setup.
  Mokrousov MD, Thompson W, Ermilov SA, Abakumova T, Novoselova MV, Inozemtseva OA, Zatsepin TS, Zharov VP, Galanzha EI, Gorin DA.Biomed Opt Express. 2021 May 7;12(6):3181-3195. doi: 10.1364/BOE.419461.

• Mesyl Phosphoramidate Oligonucleotides as Potential Splice-Switching Agents: Impact of Backbone Structure on Activity and Intracellular Localization.
  Hammond SM, Sergeeva OV, Melnikov PA, Goli L, Stoodley J, Zatsepin TS, Stetsenko DA, Wood MJA.Nucleic Acid Ther. 2021 Jun;31(3):190-200. doi: 10.1089/nat.2020.0860. 

• Phenoxazine pseudonucleotides in DNA i-motifs allow precise profiling of small molecule binders by fluorescence monitoring.
  Tsvetkov VB, Turaev AV, Petrunina NA, Melnik DM, Khodarovich YM, Pozmogova GE, Zatsepin TS, Varizhuk AM, Aralov AV.Analyst. 2021 Jul 21;146(14):4436-4440. doi: 10.1039/d1an00660f. 

• Multifunctional nanostructured drug delivery carriers for cancer therapy: Multimodal imaging and ultrasound-induced drug release.
  Novoselova MV, German SV, Abakumova TO, Perevoschikov SV, Sergeeva OV, Nesterchuk MV, Efimova OI, Petrov KS, Chernyshev VS, Zatsepin TS, Gorin DA.Colloids Surf B Biointerfaces. 2021 Apr;200:111576. doi: 10.1016/j.colsurfb.2021.111576. 

• The rise and spread of the SARS-CoV-2 AY.122 lineage in Russia. Klink GV, Safina K, Nabieva E, Shvyrev N, Garushyants S, Alekseeva E, Komissarov AB, Danilenko DM, Pochtovyi AA, Divisenko EV, Vasilchenko LA, Shidlovskaya EV, Kuznetsova NA; Coronavirus Russian Genetics Initiative (CoRGI) Consortium, Samoilov AE, Neverov AD, Popova AV, Fedonin GG; CRIE Consortium, Akimkin VG, Lioznov D, Gushchin VA, Shchur V, Bazykin GA. medRxiv. 2021 Dec 5:2021.12.02.21267168. doi: 10.1101/2021.12.02.21267168.

• Convergent Adaptation in Mitochondria of Phylogenetically Distant Birds: Does it Exist? Burskaia V, Artyushin I, Potapova NA, Konovalov K, Bazykin GA.Genome Biol Evol. 2021 Jul 6;13(7):evab113. doi: 10.1093/gbe/evab113

• Genomic epidemiology of the early stages of the SARS-CoV-2 outbreak in Russia. Komissarov AB, Safina KR, Garushyants SK, Fadeev AV, Sergeeva MV, Ivanova AA, Danilenko DM, Lioznov D, Shneider OV, Shvyrev N, Spirin V, Glyzin D, Shchur V, Bazykin GA. Nat Commun. 2021 Jan 28;12(1):649. doi: 10.1038/s41467-020-20880-z
• Episodic evolution of coadapted sets of amino acid sites in mitochondrial proteins. Neverov AD, Popova AV, Fedonin GG, Cheremukhin EA, Klink GV, Bazykin GA. PLoS Genet. 2021 Jan 25;17(1):e1008711. doi: 10.1371/journal.pgen.1008711. eCollection 2021 Jan.

• A broad comparative genomics approach to understanding the pathogenicity of Complex I mutations. Klink GV, O’Keefe H, Gogna A, Bazykin GA, Elson JL.Sci Rep. 2021 Oct 1;11(1):19578. doi: 10.1038/s41598-021-98360-7

• HLA binding of self-peptides is biased towards proteins with specific molecular functions. Karnaukhov V, Paes W, Woodhouse IB, Partridge T, Nicastri A, Brackenridge S, Scherbinin D, Chudakov DM, Zvyagin IV, Ternette N, Koohy H, Borrow P, Shugay M.bioRxiv. 2021 Feb 17:2021.02.16.431395. doi: 10.1101/2021.02.16.431395.

•  T-cell tracking, safety, and effect of low-dose donor memory T-cell infusions after αβ T cell-depleted hematopoietic stem cell transplantation. Blagov S, Zvyagin IV, Shelikhova L, Khismatullina R, Balashov D, Komech E, Fomchenkova V, Shugay M, Starichkova J, Kurnikova E, Pershin D, Fadeeva M, Glushkova S, Muzalevskii Y, Kazachenok A, Efimenko M, Osipova E, Novichkova G, Chudakov D, Maschan A, Maschan M.Bone Marrow Transplant. 2021 Apr;56(4):900-908. doi: 10.1038/s41409-020-01128-2.

• Cyanine mitochondrial dye with slightly selective cytotoxicity against A549 cancerous cells.
  Skvortsov DA, Emashova SK, Kalinina MA, Dontsova OA. Arch Pharm (Weinheim). 2021 Mar;354(3):e2000281. doi: 10.1002/ardp.202000281. 

• Panel of potential lncRNA biomarkers can distinguish various types of liver malignant and benign tumors.
  Burenina OY, Lazarevich NL, Kustova IF, Shavochkina DA, Moroz EA, Kudashkin NE, Patyutko YI, Metelin AV, Kim EF, Skvortsov DA, Zatsepin TS, Rubtsova MP, Dontsova OA. J Cancer Res Clin Oncol. 2021 Jan;147(1):49-59. doi: 10.1007/s00432-020-03378-5.

• Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene.
  Kalinina M, Skvortsov D, Kalmykova S, Ivanov T, Dontsova O, Pervouchine DD.Nucleic Acids Res. 2021 Jan 11;49(1):479-490. doi: 10.1093/nar/gkaa1208.

• Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them.
  Machulkin AE, Shafikov RR, Uspenskaya AA, Petrov SA, Ber AP, Skvortsov DA, Nimenko EA, Zyk NU, Smirnova GB, Pokrovsky VS, Abakumov MA, Saltykova IV, Akhmirov RT, Garanina AS, Polshakov VI, Saveliev OY, Ivanenkov YA, Aladinskaya AV, Finko AV, Yamansarov EU, Krasnovskaya OO, Erofeev AS, Gorelkin PV, Dontsova OA, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG.J Med Chem. 2021 Apr 22;64(8):4532-4552. doi: 10.1021/acs.jmedchem.0c01935. 

• Antibacterial activity of noscapine analogs.
  Ivanenkov YA, Yu Filyaeva K, Matniyazov RT, Baymiev AK, Baymiev AK, Vladimirova AA, Yamidanov RS, Mavzyutov AR, Zileeva ZR, Zainullina LF, Vakhitova JV, Marina VI, Terentiev VA, Osterman IA, Kartsev VG, Bezrukov DS, Dontsova OA. Bioorg Med Chem Lett. 2021 Jul 1;43:128055. doi: 10.1016/j.bmcl.2021.128055. Epub 2021 Apr 21.PMID: 33892103

• PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins.
  Savelyev NV, Shepelev NM, Lavrik OI, Rubtsova MP, Dontsova OA.Front Cell Dev Biol. 2021 May 19;9:621134. doi: 10.3389/fcell.2021.621134. 

• Single-cell Hi-C data analysis: safety in numbers.
  Galitsyna AA, Gelfand MS.Brief Bioinform. 2021 Nov 5;22(6):bbab316. doi: 10.1093/bib/bbab316.PMID: 34406348

• Structural and biochemical characterization of a novel ZntB (CmaX) transporter protein from Pseudomonas aeruginosa.
  Stetsenko A, Stehantsev P, Dranenko NO, Gelfand MS, Guskov A.Int J Biol Macromol. 2021 Aug 1;184:760-767. doi: 10.1016/j.ijbiomac.2021.06.130. Epub 2021 Jun 24.PMID: 34175341 Free article.

• Perspectives for the reconstruction of 3D chromatin conformation using single cell Hi-C data.
  Kos PI, Galitsyna AA, Ulianov SV, Gelfand MS, Razin SV, Chertovich AV.PLoS Comput Biol. 2021 Nov 18;17(11):e1009546. doi: 10.1371/journal.pcbi.1009546. eCollection 2021 Nov.

• High Rates of Genome Rearrangements and Pathogenicity of Shigella spp.
  Seferbekova Z, Zabelkin A, Yakovleva Y, Afasizhev R, Dranenko NO, Alexeev N, Gelfand MS, Bochkareva OO.Front Microbiol. 2021 Apr 12;12:628622. doi: 10.3389/fmicb.2021.628622. 
• A Retrospective Multicenter Evaluation of Eravacycline Utilization in Community and Academic Hospitals.
  Hobbs ALV, Gelfand MS, Cleveland KO, Saddler K, Sierra-Hoffman MA.J Glob Antimicrob Resist. 2021 Nov 14:S2213-7165(21)00247-2. doi: 10.1016/j.jgar.2021.10.020. 

• Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes.
  Chervova A, Fatykhov B, Koblov A, Shvarov E, Preobrazhenskaya J, Vinogradov D, Ponomarev GV, Gelfand MS, Kazanov MD.NAR Cancer. 2021 Jul 2;3(3):zcab025. doi: 10.1093/narcan/zcab025.

• Comparative Analysis of the IclR-Family of Bacterial Transcription Factors and Their DNA-Binding Motifs: Structure, Positioning, Co-Evolution, Regulon Content.
  Suvorova IA, Gelfand MS.Front Microbiol. 2021 Jun 10;12:675815. doi: 10.3389/fmicb.2021.675815. 

• Studying SARS-CoV-2 with Fluorescence Microscopy.
  Putlyaeva LV, Lukyanov KA.Int J Mol Sci. 2021 Jun 18;22(12):6558. doi: 10.3390/ijms22126558.

• Transient Fluorescence Labeling: Low Affinity-High Benefits.
  Perfilov MM, Gavrikov AS, Lukyanov KA, Mishin AS.Int J Mol Sci. 2021 Oct 30;22(21):11799. doi: 10.3390/ijms222111799.

• Computational redesign of a fluorogen activating protein with Rosetta.
  Bozhanova NG, Harp JM, Bender BJ, Gavrikov AS, Gorbachev DA, Baranov MS, Mercado CB, Zhang X, Lukyanov KA, Mishin AS, Meiler J.PLoS Comput Biol. 2021 Nov 8;17(11):e1009555. doi: 10.1371/journal.pcbi.1009555.

• Chromophore reduction plus reversible photobleaching: how the mKate2 “photoconversion” works.
  Protasova EA, Mishin AS, Lukyanov KA, Maksimov EG, Bogdanov AM.Photochem Photobiol Sci. 2021 Jun;20(6):791-803. doi: 10.1007/s43630-021-00060-8. 

• FUCCI-Red: a single-color cell cycle indicator for fluorescence lifetime imaging.
  Shirmanova MV, Gorbachev DA, Sarkisyan KS, Parnes AP, Gavrina AI, Polozova AV, Kovaleva TF, Snopova LB, Dudenkova VV, Zagaynova EV, Lukyanov KA.Cell Mol Life Sci. 2021 Apr;78(7):3467-3476. doi: 10.1007/s00018-020-03712-7.

• Impacts of OrX and cAMP-insensitive Orco to the insect olfactory heteromer activity.
  Kolesov DV, Ivanova VO, Sokolinskaya EL, Kost LA, Balaban PM, Lukyanov KA, Nikitin ES, Bogdanov AM.Mol Biol Rep. 2021 May;48(5):4549-4561. doi: 10.1007/s11033-021-06480-0. 

• Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design.
  Pletneva NV, Maksimov EG, Protasova EA, Mamontova AV, Simonyan TR, Ziganshin RH, Lukyanov KA, Muslinkina L, Pletnev S, Bogdanov AM, Pletnev VZ.Comput Struct Biotechnol J. 2021 May 11;19:2950-2959. doi: 10.1016/j.csbj.2021.05.017. 

• PDT with genetically encoded photosensitizer miniSOG on a tumor spheroid model: A comparative study of continuous-wave and pulsed irradiation.
  Yuzhakova DV, Shirmanova MV, Klimenko VV, Lukina MM, Gavrina AI, Komarova AD, Gorbachev DA, Sapogova NV, Lukyanov KA, Kamensky VA.Biochim Biophys Acta Gen Subj. 2021 Dec;1865(12):129978. doi: 10.1016/j.bbagen.2021.129978. 

• Molecular Tools for Targeted Control of Nerve Cell Electrical Activity. Part I.
  Kolesov DV, Sokolinskaya EL, Lukyanov KA, Bogdanov AM.Acta Naturae. 2021 Jul-Sep;13(3):52-64. doi: 10.32607/actanaturae.11414.

• Reduced purine biosynthesis in humans after their divergence from Neandertals.
  Stepanova V, Moczulska KE, Vacano GN, Kurochkin I, Ju X, Riesenberg S, Macak D, Maricic T, Dombrowski L, Schörnig M, Anastassiadis K, Baker O, Naumann R, Khrameeva E, Vanushkina A, Stekolshchikova E, Egorova A, Tkachev A, Mazzarino R, Duval N, Zubkov D, Giavalisco P, Wilkinson TG, Patterson D, Khaitovich P, Pääbo S.Elife. 2021 May 4;10:e58741. doi: 10.7554/eLife.58741.

• The Hitchhiker’s Guide to Untargeted Lipidomics Analysis: Practical Guidelines.
  Smirnov D, Mazin P, Osetrova M, Stekolshchikova E, Khrameeva E.Metabolites. 2021 Oct 20;11(11):713. doi: 10.3390/metabo11110713.

• Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6.
  Stein D, Mizrahi A, Golova A, Saretzky A, Venzor AG, Slobodnik Z, Kaluski S, Einav M, Khrameeva E, Toiber D.Aging (Albany NY). 2021 Mar 9;13(5):6420-6441. doi: 10.18632/aging.202755. 

• FACS-based isolation of fixed mouse neuronal nuclei for ATAC-seq and Hi-C.
  Eremenko E, Golova A, Stein D, Einav M, Khrameeva E, Toiber D.STAR Protoc. 2021 Jul 9;2(3):100643. doi: 10.1016/j.xpro.2021.100643. 

• TP73-AS1 is induced by YY1 during TMZ treatment and highly expressed in the aging brain.
  Mazor G, Smirnov D, Ben David H, Khrameeva E, Toiber D, Rotblat B.Aging (Albany NY). 2021 Jun 11;13(11):14843-14861. doi: 10.18632/aging.203182.

• Long-Term Fluoxetine Administration Causes Substantial Lipidome Alteration of the Juvenile Macaque Brain.
  Tkachev A, Stekolshchikova E, Bobrovskiy DM, Anikanov N, Ogurtsova P, Park DI, Horn AKE, Petrova D, Khrameeva E, Golub MS, Turck CW, Khaitovich P.Int J Mol Sci. 2021 Jul 28;22(15):8089. doi: 10.3390/ijms22158089.

• An extended catalogue of tandem alternative splice sites in human tissue transcriptomes.
  Mironov A, Denisov S, Gress A, Kalinina OV, Pervouchine DD.PLoS Comput Biol. 2021 Apr 7;17(4):e1008329. doi: 10.1371/journal.pcbi.1008329

• IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck Cancer.
  Badarni M, Prasad M, Golden A, Bhattacharya B, Levin L, Yegodayev KM, Dimitstein O, Joshua BZ, Cohen L, Khrameeva E, Kong D, Porgador A, Braiman A, Grandis JR, Rotblat B, Elkabets M.Cancers (Basel). 2021 May 7;13(9):2250. doi: 10.3390/cancers13092250.

• Biological evaluation and spectral characterization of a novel tetracenomycin X congener.
  Alferova VA, Maviza TP, Biryukov MV, Zakalyukina YV, Lukianov DA, Skvortsov DA, Vasilyeva LA, Tashlitsky VN, Polshakov VI, Sergiev PV, Korshun VA, Osterman IA.

• Functional Diversity of Mitochondrial Peptidyl-tRNA Hydrolase ICT1 in Human Cells.
  Chicherin IV, Dukhalin SV, Khannanov RA, Baleva MV, Levitskii SA, Patrushev MV, Sergiev PV, Kamenski P.Front Mol Biosci. 2021 Jul 16;8:716885. doi: 10.3389/fmolb.2021.716885. 

• Quality Control Mechanisms in Bacterial Translation.
  Zarechenskaia AS, Sergiev PV, Osterman IA.Acta Naturae. 2021 Apr-Jun;13(2):32-44. doi: 10.32607/actanaturae.11401.

• Little but Loud. The Diversity of Functions of Small Proteins and Peptides – Translational Products of Short Reading Frames.
  Sergiev PV, Rubtsova MP.Biochemistry (Mosc). 2021 Sep;86(9):1139-1150. doi: 10.1134/S0006297921090091.

• The bacteriophage LUZ24 “Igy” peptide inhibits the Pseudomonas DNA gyrase.
  De Smet J, Wagemans J, Boon M, Ceyssens PJ, Voet M, Noben JP, Andreeva J, Ghilarov D, Severinov K, Lavigne R.Cell Rep. 2021 Aug 24;36(8):109567. doi: 10.1016/j.celrep.2021.109567.

• Prespacers formed during primed adaptation associate with the Cas1-Cas2 adaptation complex and the Cas3 interference nuclease-helicase.
  Musharova O, Medvedeva S, Klimuk E, Guzman NM, Titova D, Zgoda V, Shiriaeva A, Semenova E, Severinov K, Savitskaya E.Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2021291118. doi: 10.1073/pnas.2021291118.

• Protospacer-Adjacent Motif Specificity during Clostridioides difficile Type I-B CRISPR-Cas Interference and Adaptation.
  Maikova A, Boudry P, Shiriaeva A, Vasileva A, Boutserin A, Medvedeva S, Semenova E, Severinov K, Soutourina O.mBio. 2021 Aug 31;12(4):e0213621. doi: 10.1128/mBio.02136-21. 

• Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition.
  Dimitriu T, Kurilovich E, Łapińska U, Severinov K, Pagliara S, Szczelkun MD, Westra ER.Cell Host Microbe. 2021 Dec 14:S1931-3128(21)00520-5. doi: 10.1016/j.chom.2021.11.014. 

• The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy.
  Cui Z, Liu H, Zhang H, Huang Z, Tian R, Li L, Fan W, Chen Y, Chen L, Zhang S, Das BC, Severinov K, Hitzeroth II, Debata PR, Jin Z, Liu J, Huang Z, Xie W, Xie H, Lang B, Ma J, Weng H, Tian X, Hu Z.Mol Ther Nucleic Acids. 2021 Aug 19;26:1466-1478. doi: 10.1016/j.omtn.2021.08.008. 

• Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from Bacillus thuringiensis sv. andalousiensis.
  Grigoreva A, Andreeva J, Bikmetov D, Rusanova A, Serebryakova M, Garcia AH, Slonova D, Nair SK, Lippens G, Severinov K, Dubiley S.iScience. 2021 Apr 29;24(5):102480. doi: 10.1016/j.isci.2021.102480.

• New insights into the diversity and evolution of the archaeal mobilome from three complete genomes of Saccharolobus shibatae.
  Medvedeva S, Brandt D, Cvirkaite-Krupovic V, Liu Y, Severinov K, Ishino S, Ishino Y, Prangishvili D, Kalinowski J, Krupovic M.Environ Microbiol. 2021 Aug;23(8):4612-4630. doi: 10.1111/1462-2920.15654. 

• Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA.
  Shebanova R, Nikitchina N, Shebanov N, Mekler V, Kuznedelov K, Ulashchik E, Vasilev R, Sharko O, Shmanai V, Tarassov I, Severinov K, Entelis N, Mazunin I.Nucleic Acids Res. 2021 Dec 24:gkab1227. doi: 10.1093/nar/gkab1227. 

• SCRAMBLER: A Tool for De Novo CRISPR Array Reconstruction and Its Application for Analysis of the Structure of Prokaryotic Populations.
  Rykachevsky A, Stepakov A, Muzyukina P, Medvedeva S, Dobrovolski M, Burnaev E, Severinov K, Savitskaya E.CRISPR J. 2021 Oct;4(5):673-685. doi: 10.1089/crispr.2021.0012.PMID: 34661428

• Non-homologous dsODN increases the mutagenic effects of CRISPR-Cas9 to disrupt oncogene E7 in HPV positive cells.
  Fan W, Yu M, Wang X, Xie W, Tian R, Cui Z, Jin Z, Huang Z, Das BC, Severinov K, Hitzeroth II, Debata PR, Tian X, Xie H, Lang B, Tan J, Xu H, Hu Z.Cancer Gene Ther. 2021 Jun 10. doi: 10.1038/s41417-021-00355-z. 

• Uncertainty-aware and interpretable evaluation of Cas9-gRNA and Cas12a-gRNA specificity for fully matched and partially mismatched targets with Deep Kernel Learning.
  Kirillov B, Savitskaya E, Panov M, Ogurtsov AY, Shabalina SA, Koonin EV, Severinov KV.Nucleic Acids Res. 2021 Nov 17:gkab1065. doi: 10.1093/nar/gkab1065. 

• Structure and function of virion RNA polymerase of a crAss-like phage.
  Drobysheva AV, Panafidina SA, Kolesnik MV, Klimuk EI, Minakhin L, Yakunina MV, Borukhov S, Nilsson E, Holmfeldt K, Yutin N, Makarova KS, Koonin EV, Severinov KV, Leiman PG, Sokolova ML.Nature. 2021 Jan;589(7841):306-309. doi: 10.1038/s41586-020-2921-5. Epub 2020 Nov 18

• Computational models in the service of X-ray and cryo-electron microscopy structure determination.

  Kryshtafovych A, Moult J, Albrecht R, Chang GA, Chao K, Fraser A, Greenfield J, Hartmann MD, Herzberg O, Josts I, Leiman PG, Linden SB, Lupas AN, Nelson DC, Rees SD, Shang X, Sokolova ML, Tidow H; AlphaFold2 team.Proteins. 2021 Dec;89(12):1633-1646. doi: 10.1002/prot.26223. Epub 2021 Sep 6.PMID: 34449113

• Inhibition of hyaluronan secretion by novel coumarin compounds and chitin synthesis inhibitors.
  Tsitrina AA, Krasylov IV, Maltsev DI, Andreichenko IN, Moskvina VS, Ivankov DN, Bulgakova EV, Nesterchuk M, Shashkovskaya V, Dashenkova NO, Khilya VP, Mikaelyan A, Kotelevtsev Y.Glycobiology. 2021 Sep 9;31(8):959-974. doi: 10.1093/glycob/cwab038.

•  Naïve Regulatory T Cell Subset Is Altered in X-Linked Agammaglobulinemia. Shelyakin PV, Lupyr KR, Egorov ES, Kofiadi IA, Staroverov DB, Kasatskaya SA, Kriukova VV, Shagina IA, Merzlyak EM, Nakonechnaya TO, Latysheva EA, Manto IA, Khaitov MR, Lukyanov SA, Chudakov DM, Britanova OV.Front Immunol. 2021 Aug 19;12:697307. doi: 10.3389/fimmu.2021.697307.