2015

Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues. Bozek K, Wei Y, Yan Z, Liu X, Xiong J, Sugimoto M, Tomita M, Pääbo S, Sherwood C, Hof P, Ely J, Li Y, Steinhauser D, Willmitzer L, Giavalisco P, Khaitovich P. Neuron. 2015 Feb 18;85(4):695-702. doi: 10.1016/j.neuron.2015.01.003.

Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. Wei Y, Hu H, Xie G, Fu N, Ning Z, Zeng R, Khaitovich P. Genome Biol. 2015 Feb 22;16:41. doi: 10.1186/s13059-015-0608-2.

Use of RNA polymerase molecular beacon assay to measure RNA polymerase interactions with model promoter fragments. Mekler V, Severinov K. Methods Mol Biol. 2015;1276:199-210. doi: 10.1007/978-1-4939-2392-2_11.

Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists. Chiellini G, Nesi G, Digiacomo M, Malvasi R, Espinoza S, Sabatini M, Frascarelli S, Laurino A, Cichero E, Macchia M, Gainetdinov R, Fossa P, Raimondi L, Zucchi R, Rapposelli S. J Med Chem. 2015 Jun 5.

Dopamine receptors – IUPHAR Review 13. Beaulieu J, Espinoza S, Gainetdinov R. Br J Pharmacol. 2015 Jan;172(1):1-23.

The trace amine-associated receptor 1 modulates methamphetamine’s neurochemical and behavioral effects. Cotter R, Pei Y, Mus L, Harmeier A, Gainetdinov R, Hoener M, Canales J. Front Neurosci. 2015 Feb 13;9:39. doi: 10.3389/fnins.2015.00039. eCollection 2015.

TAAR1 Modulates Cortical Glutamate NMDA Receptor Function. Espinoza S, Lignani G, Caffino L, Maggi S, Sukhanov I, Leo D, Mus L, Emanuele M, Ronzitti G, Harmeier A, Medrihan L, Sotnikova T, Chieregatti E, Hoener MC, Benfenati F, Tucci V, Fumagalli F, Gainetdinov R. 2015 Mar 9. doi: 10.1038/npp.2015.65.

Postsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1. Espinoza S, Ghisi V, Emanuele M, Leo D, Sukhanov I, Sotnikova T, Chieregatti E, Gainetdinov R. Neuropharmacology. 2015 Jun;93:308-13. doi: 10.1016/j.neuropharm.2015.02.010. Epub 2015 Feb 24.

G protein-coupled receptor kinases: from molecules to diseases. Gurevich E, Premont R, Gainetdinov R. FASEB J. 2015 Feb;29(2):361-4. doi: 10.1096/fj.14-263657ufm

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits. Masoud S, Vecchio L, Bergeron Y, Hossain M, Nguyen L, Bermejo M, Kile B, Sotnikova T, Siesser W, Gainetdinov R, Wightman R, Caron M, Richardson J, Miller G, Ramsey A, Cyr M, Salahpour A , Neurobiol Dis. 2015 Feb;74:66-75. doi: 10.1016/j.nbd.2014.10.016.

Bacteriophage Xp10 anti-termination factor p7 induces forward translocation by host RNA polymerase. Zenkin N, Severinov K, Yuzenkova Y. Nucleic Acids Res. 2015 Jun 1. pii: gkv586.

The Cas6e ribonuclease is not required for interference and adaptation by the E. coli type I-E CRISPR-Cas system. Semenova E, Kuznedelov K, Datsenko K, Boudry P, Savitskaya E, Medvedeva S, Beloglazova N, Logacheva M, Yakunin AF, Severinov K. Nucleic Acids Res. 2015 May 26. pii: gkv546.

Rapid Multiplex Creation of Escherichia coli Strains Capable of Interfering with Phage Infection Through CRISPR. Strotksaya A, Semenova E, Severinov K. Methods Mol Biol. 2015;1311:147-59. doi: 10.1007/978-1-4939-2687-9_9.

RNA polymerase molecular beacon as tool for studies of RNA polymerase-promoter interactions. Mekler V, Severinov K. Methods. 2015 May 5. pii: S1046-2023(15)00180-2. doi: 10.1016/j.ymeth.2015.04.033.

Functional analysis of C1 family cysteine peptidases in the larval gut of Тenebrio molitor and Tribolium castaneum. Martynov A, Elpidina E, Perkin L, Oppert B. BMC Genomics. 2015 Feb 14;16:75. doi: 10.1186/s12864-015-1306-x.

Distinct pathways of RNA polymerase regulation by a phage-encoded factor. Esyunina D, Klimuk E, Severinov K, Kulbachinskiy A. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2017-22. doi: 10.1073/pnas.1416330112. Epub 2015 Feb 2.

Enzymatic Synthesis and Functional Characterization of Bioactive Microcin C-Like Compounds with Altered Peptide Sequence and Length. Bantysh O, Serebryakova M, Zukher I, Kulikovsky A, Tsibulskaya D, Dubiley S, Severinov K. J Bacteriol. 2015 Oct 1;197(19):3133-41. doi: 10.1128/JB.00271-15. Epub 2015 Jul 20.

Active Nuclear Import of Membrane Proteins Revisited. Laba J, Steen A, Popken P, Chernova A, Poolman B, Veenhoff LM. 2015 Oct 13;4(4):653-73. doi: 10.3390/cells4040653.

In-vivo pharmacology of Trace-Amine Associated Receptor 1. Lam V, Espinoza S, Gerasimov A, Gainetdinov R, Salahpour A. Eur J Pharmacol. 2015 Sep 15;763(Pt B):136-42. doi: 10.1016/j.ejphar.2015.06.026. Epub 2015 Jun 17.

A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophage. Yakunina M, Artamonova T, Borukhov S, Makarova K, Severinov K, Minakhin L. Nucleic Acids Res. 2015 Dec 2;43(21):10411-20. doi: 10.1093/nar/gkv1095. Epub 2015 Oct 20.

CRISPR interference and priming varies with individual spacer sequences. Xue C, Seetharam A, Musharova O, Severinov K, J Brouns S, Severin A, Sashital D. Nucleic Acids Res. 2015 Dec 15;43(22):10831-47. doi: 10.1093/nar/gkv1259. Epub 2015 Nov 19.

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems. Shmakov S, Abudayyeh O, Makarova K, Wolf I, Gootenberg J, Semenova E, Minakhin L, Joung J, Konermann S, Severinov K, Zhang F, Koonin EV. Mol Cell. 2015 Nov 5;60(3):385-97. doi: 10.1016/j.molcel.2015.10.008. Epub 2015 Oct 22.

Increased context-dependent conditioning to amphetamine in mice lacking TAAR1. Sukhanov I, Caffino L, Efimova E, Espinoza S, Sotnikova T, Cervo L, Fumagalli , Gainetdinov R. Pharmacol Res. 2015 Dec 2;103:206-214. doi: 10.1016/j.phrs.2015.11.002.

Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery. Vorontsova D, Datsenko K, Medvedeva S, Bondy-Denomy J, Savitskaya E, Pougach K, Logacheva M, Wiedenheft B, Davidson A, Severinov K, Semenova E. Nucleic Acids Res. 2015 Dec 15;43(22):10848-60. doi: 10.1093/nar/gkv1261. Epub 2015 Nov 19.

Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system. Morozova N, Sabantsev A, Bogdanova E, Fedorova Y, Maikova A, Vedyaykin A, Rodic A, Djordjevic M, Khodorkovskii M, Severinov K. Nucleic Acids Res. 2015 Dec 19. pii: gkv1490.

Tumor heterogeneity-induced signaling regulates SCLC metastasis. Kwon M, Berns A. Cell Cycle. 2015;14(21):3347-8. doi: 10.1080/15384101.2015.1093445.

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis. Kwon M, Proost N, Song J, Sutherland K, Zevenhoven J, Berns A. Genes Dev. 2015 Aug 1;29(15):1587-92. doi: 10.1101/gad.262998.115.

Wnt Down, Tumors Wind Up? Krimpenfort P, Berns A. Cell. 2015 Jun 18;161(7):1494-6. doi: 10.1016/j.cell.2015.06.008.

Regulation of Liver Metabolism by the Endosomal GTPase Rab5. Zeigerer A, Bogorad L, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D’Souza C, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, Holzhütter HG, Shevchenko A, Mann M, Koteliansky V, Zerial M. Cell Rep. 2015 May 12;11(6):884-92. doi: 10.1016/j.celrep.2015.04.018. 2015 Apr 30.

Identification of siRNA delivery enhancers by a chemical library screen. Gilleron J, Paramasivam P, Zeigerer A, Querbes W, Marsico G, Andree C, Seifert S, Amaya P, Stöter M, Koteliansky V, Waldmann H, Fitzgerald K, Kalaidzidis Y, Akinc A, Maier MA, Manoharan M, Bickle M, Zerial M. Nucleic Acids Res. 2015 Sep 18;43(16):7984-8001. doi: 10.1093/nar/gkv762. Epub 2015 Jul 28.

Skeletal muscle as an endocrine organ: Role of [Na+]i/[K+]i-mediated excitation-transcription coupling. Kapilevich L, Kironenko T, Zaharova A, Kotelevtsev Y, Dulin N, Orlov S. Genes Dis. 2015 Dec;2(4)

Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice. Padrissa-Altés S, Bachofner M, Bogorad R, Pohlmeier L, Rossolini T, Böhm F, Liebisch G, Hellerbrand C, Koteliansky V, Speicher T, Werner S. Gut. 2015 Sep;64(9):1444-53.

Steroid promiscuity: Diversity of enzyme action. Preface. Lathe R, Kotelevtsev Y, Mason J. J Steroid Biochem Mol Biol. 2015 Jul; 151:1-2. doi: 10.1016/j.jsbmb.2015.01.008. 2015 Jan 14.

Innate immunity: Bacterial cell-wall muramyl peptide targets the conserved transcription factor YB-1. Laman A, Lathe R, Savinov G, Shepelyakovskaya A, Boziev K, Baidakova L, Chulin A, Brovko F, Svirshchevskaya E, Kotelevtsev Y, Eliseeva I, Guryanov S, Lyabin D, Ovchinnikov L, Ivanov V. FEBS Lett. 2015 Jul 8; 589(15):1819-24. doi: 0.1016/j.febslet.2015.05.028. Epub 2015 May 27.

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins. Piatkov K, Tri T. M. Vu, Hwang C, Varshavsky A. Microbial Cell 2015

TERRA mimicking ssRNAs prevail over the DNA substrate for telomerase in vitro due to interactions with the alternative binding site. Azhibek D, Skvortsov D, Andreeva A, Zatsepin T, Arutyunyan A, Zvereva M, Dontsova O. J Mol Recognit. 2015 Dec 16. doi: 10.1002/jmr.2521

Solid- and solution-phase synthesis and application of R6G dual-labeled oligonucleotide probes. Skoblov A, Vichuzhanin M, Farzan V, Veselova O, Konovalova T, Podkolzin A, Shipulin G, Zatsepin T. Bioorg Med Chem. 2015 Oct 15;23(20):6749-56. doi: 10.1016/j.bmc.2015.08.041. Epub 2015 Sep 1.

Oligonucleotide inhibitors of telomerase: prospects for anticancer therapy and diagnostics. Zvereva M, Zatsepin T, Azhibek D, Shubernetskaya O, Shpanchenko O, Dontsova O. Biochemistry (Mosc). 2015 Mar