Recent Advances in Spectroscopic Imaging

Speaker: Prof. Sergei Kazarian sergei-kazarian-seminar-recenet-advances-in-spectrosocpic-imaging-1
 
WHEN: October, 15 2018 (Monday) at 11.00
WHERE: Skoltech, Nobel 3, Room 303

SEMINAR ABSTRACT: This talk will present our recent research in FTIR spectroscopic imaging, Chemical visualisation with enhanced spatial resolution in micro ATR imaging mode broadens the range of samples amenable to study with FTIR imaging which were previously ruled out by the inadequate spatial resolution. The opportunity to obtain chemical images of the same sample from different depths through the use of micro ATR-FTIR imaging with variable angles of incidence has also been demonstrated. In FTIR spectroscopic imaging in transmission mode, a novel “pseudo-hemisphere” approach was introduced and demonstrated increased spatial resolution along with the removal of chromatic aberration and a reduction in scattering. We show that this approach can be applied to image biomaterials and cancer tissues in transmission mode without chromatic aberration and with an improvement in spatial resolution. In a further development, a second set of lens to create pseudo sphere was introduced to obtain focused images of live cells in microfluidic devices without the recourse to a synchrotron source of infrared radiation. Chemical imaging at nanoscale and studies of single molecules is possible using tip-enhanced Raman spectroscopy and a recent research will be summarized.

SPEAKER INTRODUCTION: Dr. Sergei G. Kazarian is Professor of Physical Chemistry at the Department of Chemical Engineering of Imperial College London and a visiting professor at Tokyo Institute of Technology. Professor Kazarian is a Fellow of the Royal Society of Chemistry and a Fellow of Society for Applied Spectroscopy. He is Editorin- Chief of Applied Spectroscopy. His PhD in Physical Chemistry is from the Academy of Sciences in Moscow and he joined Imperial College London in 1998. His research encompasses the fields of vibrational spectroscopy, intermolecular interactions, ionic liquids and materials. Most of his recent research is focused on FTIR spectroscopic imaging and its applications for characterisation of polymeric, pharmaceutical, forensic and biomedical systems. He has pioneered and developed new approaches and applications in FTIR imaging and in particular, ATR-FTIR spectroscopic imaging. His current research interests also include confocal Raman microscopy and tip-enhanced Raman scattering for materials characterisation. Dr. Kazarian published over 240 articles and he collaborates with scientists around the world, including active collaboration with institutes and universities in Novosibirsk (following a project funded by Skolkovo Foundation) and Kazan (Optics and Nanophotonics) He was awarded the Sir George Stokes Award in 2015 by the Royal Society.