Matvei Kolesnik

Research advisor: Professor Konstantin Severinov

Program entry year: 2017

Graduated from MSU, Biological Faculty in 2017

Research project: An RNA-Seq based investigation of in vivo activity of CRISPR-Cas system type VI

Research interests:  mobile genetic elements in evolution,  CRISPR-Cas systems, phage-host interaction

Industry Immersion:
Company: Sirius

Project: “Searching for protection mechanisms against CRISPR-Cas bacterial systems”

Publications:

Lopatina, A., Medvedeva, S., Artamonova, D., Kolesnik, M., Sitnik, V., Ispolatov, Y., & Severinov, K. (2019). Natural diversity of CRISPR spacers of Thermus: evidence of local spacer acquisition and global spacer exchange. Philosophical Transactions of the Royal Society B, 374(1772), 20180092. doi: 10.1098/rstb.2018.0092

Artamonova, D., Karneyeva, K., Medvedeva, S., Klimuk, E., Kolesnik, M., Yasinskaya, A., Samolygo, A., & Severinov, K. (2020). Spacer acquisition by Type III CRISPR-Cas system during bacteriophage infection of Thermus thermophilus. Nucleic Acids Research, gkaa685. doi: 10.1093/nar/gkaa685

Drobysheva, A., Panafidina, S., Kolesnik, M., Klimuk, E., Minakhin, L., Yakunina, M., Borukhov, S., Nilsson, E., Holmfeldt, K., Yutin, N., Makarova, K., Koonin, E., Severinov, K., Leiman, P., & Sokolova, M. (2020). Structure and function of virion RNA polymerase of crAss-like phage. Nature, 589, 306–309. doi: 10.1038/s41586-020-2921-5