Marina Pak

Research advisor: Dmitry Ivankov

Program entry year: 2020

Graduated from: Far Eastern Federal University, Department of Organic Chemistry in 2018 (BSc); Skoltech, Life Sciences in 2020 (MSc)

PhD project: Prediction of Protein Stability Change Upon Mutation using Deep Learning

Research interests: protein design

Publications:

• Pak, M. A., & Ivankov, D. N. (2022). Best templates outperform homology models in predicting the impact of mutations on protein stability. Bioinformatics. https://doi.org/10.1093/bioinformatics/btac515
• Pak M., Markhieva K, Novikova M., Petrov D., Vorobyev I., Maksimova E., Kondrashov F., Ivankov D. (2021). Using AlphaFold to predict the impact of single mutations on protein stability and function. bioRxiv 2021.09.19.460937; https://doi.org/10.1101/2021.09.19.460937

Conferences:

• Study of influence of homology modeling on the prediction of protein stability change upon mutation​. Marina A. Pak, Dmitry N. Ivankov. MCCMB, Skoltech, Moscow, 2021 July 30 – August 2. Poster presentation.
• AlphaFold: Does it Predict or Recognize the Protein Structure? Dmitry N. Ivankov, Marina A. Pak, Alexei V. Finkelstein. XXVIII Symposium on Bioinformatics and Computer-Aided Drug Discovery, Moscow, 2022 May 24 – 26. Oral presentation.