Artem Mikelov

Research advisor: Associate Professor Dmitry Chudakov

Program entry year: 2018

Graduated from:
Higher School of Economics in 2012 (Bachelor of Business Administration)
Financial University under the Government of Russian Federation in 2014 (Master of Innovation Management and Entrepreneurship)
Skolkovo Institute of Science and Technology in 2018 (MS in Biotechnology)

Thesis title: Dynamics of immunoglobulin repertoires in memory and antibody-secreting B cell subsets in health and disease

Research interests: adaptive immunity repertoires, allergy, autoimmunity, high-throughput sequencing

Publications:

• Pogorelyy MV, Fedorova AD, McLaren JE, Ladell K, Bagaev DV, Eliseev AV, Mikelov AI, Koneva AE, Zvyagin IV, Price DA, Chudakov DM, Shugay M. Exploring the pre-immune landscape of antigen-specific T cells. // Genome Med. 2018;10(1):68. doi: 10.1186/s13073-018-0577-7.
• A.I. Mikelov, D. B. Staroverov, E. A. Komech, Yu. B. Lebedev, D. M. Chudakov and I. V. Zvyagin (2019), “Correlated dynamics of serum IGE and IGE+ clonotype count with allergen air level in seasonal allergic rhinitis”, Bulletin of RSMU, no. 5, p. 13–22. https://doi.org/10.24075/brsmu.2019.072
• E. I. Kovalenko, I.V. Zvyagin, M.A. Streltsova, A.I. Mikelov, S.A. Erokhina, W.G. Telford, A.M. Sapozhnikov, Y.B. Lebedev. Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood //Frontiers Imm. 2020 Feb 16 https://doi.org/10.3389/fimmu.2020.613882

Conference presentations:

• Immunoglobulin heavy-chain repertoire profiling of memory B cell, plasmablasts and plasma cells from peripheral blood of individuals with birch pollen allergy. A. I. Mikelov, M. A. Turchaninova, E. A. Komech, E. S. Egorov, D. B. Staroverov, Y. B. Lebedev, D. M. Chudakov, I. V. Zvyagin. 5th European Congress of Immunology,  Amsterdam, Netherlands, 2018, September 2-5, Abstract Book, p.408. Poster presentation
• Longitudinal Profiling Of Immunoglobulin Heavy-Chain Repertoires In Memory B-Cells, Plasmablasts And Plasma Cells From Peripheral Blood Of Individuals With Birch Pollen Allergy. Mikelov A. I., Turchaninova M.A., Komech E.A., Staroverov D.B., Shvets S.M., Lebedev Y.B., Chudakov D.M., Zvyagin I.V. // WAO International Scientific Conference 2018 “PERSONALIZED MEDICINE IN ALLERGY: BIOLOGICS & IMMUNOTHERAPY”, World Allergy Organization, Florence, Italy, 2018, December 6-9. Poster presentation
• Longitudinal Immunoglobulin Heavy-Chain Repertoire Profiling Of Memory B Cell, Plasmablasts And Plasma Cells From Peripheral Blood Of Individuals With Birch Pollen Allergy. Mikelov A. I. , Turchaninova M.A., Komech E.A., Staroverov D.B., Shvets S.M., Lebedev Y.B., Chudakov D.M., Zvyagin I.V. 17th EAACI Immunology Winter School, European Academy of Allergy and Clinical Immunology (EAACI), Trysil, Norway, 2019 January 24 – 27. Poster presentation
• Longitudinal Immunoglobulin Heavy-Chain Repertoire Profiling Of Memory B Cell, Plasmablasts And Plasma Cells From Peripheral Blood Of Individuals With Birch Pollen Allergy. Mikelov A. I. , Turchaninova M.A., Komech E.A., Staroverov D.B., Shvets S.M., Lebedev Y.B., Chudakov D.M., Zvyagin I.V.  European Academy of Allergy and Clinical ImmunologyAnnual Congress 2019, Lisbon, Portugal, 2019, June 1-5.  Poster and oral presentation https://doi.org/10.1111/all.13959
  
• Seasonal Dynamics In CD4 T-Cell Receptor Repertoires In Birch Pollen Allergy. Mikelov A. I.,  Komech E.A., Lebedev Y.B., Zvyagin I.V. Antwerp TCR meeting 2019, Antwerp, Belgium, 2019, December, 9-10. Oral presentation
• European Academy of Allergy and Clinical Immunology Digital Congress 2020, ePoster — p. 68, № 1486 https://doi.org/10.1111/all.14506

Grants:

• 2016-2018 – UMNIK grant “Development of novel methods and software for allergy diagnostics and prediction, based on B-cell receptors repertoire analysis by means of next generation sequencing”