Alina Galivondzhyan

Research advisor: Professor Konstantin Severinov

Program entry year: 2021

Graduated from MSU, Faculty of Bioengineering and Bioinformatics in 2021

Research project:

Research interests: DNA topology, topoisomerases, transcription, topoisomerase:RNA-polymerase interaction

Publications:

Sutormin, D. A., Galivondzhyan, A. K., Polkhovskiy, A. V., Kamalyan, S. O., Severinov, K. V., & Dubiley, S. A. (2021). Diversity and Functions of Type II Topoisomerases. Acta naturae, 13(1), 59–75. https://doi.org/10.32607/actanaturae.11058

Zinovkina, L. A., Galivondzhyan, A. K., Prikhodko, A. S., Galkin, I. I., & Zinovkin, R. A. (2020). Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α. PeerJ, 8, e8803. https://doi.org/10.7717/peerj.8803

Conference presentations:
EMBO DNA Topology in genomic transactions. September 2021. Alina Galivondzhyan, Dmitry Sutormin, Sergey Borukhov, Konstantin Severinov. “Interaction between E. coli RNA polymerase and topoisomerase I is essential to prevent R-loop accumulation.”

Oral presentation at XXVIII International conference for students, graduate students and young scientists “Lomonosov”. April 2021. Alina Galivondzhyan, Dmitry Sutormin, Konstantin Severinov. “RNAP:EcTopoI interaction is essential to prevent R-loops formation in Escherichia coli.”

Report coauthor at XXVIII International conference for students, graduate students and young scientists “Lomonosov”. April 2021. Dmitry Sutormin, Alina Galivondzhyan, Konstantin Severinov. “Genome-wide search for E. coli topoisomerase I DNA binding and cleavage motifs using ChIP-Seq and Topo-Seq methods.”

Oral presentation at XXVII International conference for students, graduate students and young scientists “Lomonosov”. November 2020. Alina Galivondzhyan, Dmitry Sutormin, Konstantin Severinov. “Identification of topoisomerase I binding sites and study of it’s role in trascriptional regulation in Escherichia coli“.

Poster presentation at 2nd MSU and Tokyo Institute of Tecnology (TIT) conference. September 2019. Alina Galivondzhyan, Dmitry Sutormin. “Identification of topoisomerase I binding and activity sites in E. coli.”

Oral presentation at MSU 15th Student conference. April 2018. Alina Galivondzhyan, Ludmila Zinovkina. “Effect of tryphenilphosphonium derivatives on human breast adenocarcinoma cells proliferation activity.”

Poster presentation at MSU 14th Student conference. April 2017. Alina Galivondzhyan, Ludmila Zinovkina. “Mitochondria-targeted antioxidant SkQ1 increases expression of several estrogen-dependent genes.”