vitastepanova

Vita Stepanova

PhD student

Supervisor – Philipp Khaitovich.

Entry year – 2014

Vita graduated from Lomonosov Moscow State University, Department of Bioengineering and Bioinformatics. Diploma: “Genomic analysis of transcription factor regulons in Enterobacteria”.

Supervisors: Dmitry A. Rodionov, Mikhail S. Gelfand

Research project – “Integrative analysis of molecular organization of functionally distinct neocortical regions”.

Why is it cool?

Distinct areas of mammalian cerebral cortex (neocortex) are known to be involved in specific cognitive functions. However, the entire neocortex anatomically displays the same evolutionary conserved laminar architecture, which shows only slight differences in histological organization between functionally distinct regions. Similar phenomenon is observed at the level of gene expression: only slight differences in transcriptome organization are seen across neocortical regions. Furthermore, functionary boundaries between neocortical regions, although real, are dynamic: a region can take over an unusual function, for instance, as a result of injury of the original functional area. This project is planned to elucidate molecular basis underlying distinct functionality of specific brain regions by integrative bioinformatic analysis.

  1. Shkurnikov MU, Stepanova VV, Nechaev IN, Khaustova NA, Tonevitsky EA (2013) The role of peptidoglycan-recognition proteins in innate immunity. Biotechnologiya, 1
  2. Stepanova VV, Gelfand MS. (2014) RNA editing. The classical cases and the outlook of new technologies. Mol. Biol. (Mosk), 48 (1).
  3. Flegontov P, Changmai P, Zidkova A, Logacheva MD, Altınışık NE, Flegontova O, Gelfand MS, Gerasimov ES, Khrameeva EE, Konovalova OP, Neretina T, Nikolsky YV, Starostin G, Stepanova VV, Travinsky IV, Tříska M, Tříska P, Tatarinova TV. (2016) Genomic study of the Ket: a Paleo-Eskimo-related ethnic group with significant ancient North Eurasian ancestry. Sci Rep., 6.
  4. Leyn S., Suvorova, Kazakov A., Ravcheev D., Stepanova V, Novichkov P, Rodionov D. (2016) Comparative genomics and evolution of transcriptional regulons in Proteobacteria. Microbial Genomics, 2.
konstantinseverinov
Konstantin Severinov Professor, Director of the Center for Data-Intensive Biomedicine and Biotechnology
dmitripapatsenko
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dmitripervouchine
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georgiibazykin
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mikhailgelfand
Mikhail Gelfand Professor
philippkhaitovich
vladimirzelman
Vladimir Zelman Professor
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